성견에서 MyDas Joy-1Ⓡ 임플란트의 발치즉시 식립 후 골-임플란트의 계면에 대한 조직형태계측학적 평가

Abstract

ABSTRACT

Histomorphometric evaluation of bone-implant interface after immediate implantation of MyDas Joy-1Ⓡ implant in dogs

Chang-Kyu Lee Advisor : Prof. Kim Byung-Ock, D.D.S., Ph.D. Department of Dentistry, Graduate School Chosun University.

OBJECTIVE: The objective of this study was to evaluate the osseointegration of MyDas Joy-1Ⓡ implant (DAS tech, Korea) following immediate placement in mandibular extraction sockets of mongrel dogs.

MATERIALS ANDMETHODS: The 3rd and 4th mandibular premolars of 6 mongrel dogs were extracted, and then a total of 12 transmucosal screw-shaped implants were placed in each mandibular extracted socket area. Each implant has a sandblasted, large-grit, and acid etched (SLA) surface. ITI-SLAⓇ(10.0 mm length, 4.1 mm width) was used as the control group and MyDas Joy-1Ⓡ implant (10.0 mm length, 4.0 mm width) was used as the experimental group. Implants of 8-week group were placed first, and then 4-week group implants were placed 4 weeks later. The implants were left to be healed for 4 or 8 weeks. At the end of the experiment, the dogs were sacrificed and each implant sites were dissected and processed for histomorphometric analysis. The percentage of the bone-implant contact (BIC) and new bone formation area (NB) area were evaluated in both groups. Statistical analyses were performed using Mann-Whitney U test and Wilcoxon rank test. Stability test was also executed on both experimental group and control group using PeriotestⓇ immediate after installation and before sacrifice.

RESULTS: Histomorphometrical analysis showed direct osseous integration for both implants. Mean of BIC was 68.00 ± 14.33% at 4 weeks and 85.80 ± 1.78% at 8 weeks after implantation for ITI-SLAⓇ implant, and 56.40 ± 5.27% at 4 weeks and 69.80 ± 9.73% at 8 weeks for MyDas Joy-1Ⓡ implant. Mean of BI was 53.20 ± 12.73% at 4 weeks and 47.20 ± 2.68% at 8 weeks after implantation for ITI-SLAⓇ implant, and 67.00 ± 17.97% and 68.00 ± 19.35% at corresponding time intervals for MyDas Joy-1Ⓡ implant. No significant difference between both types of implants could be detected after 4 and 8 weeks of healing periods in NB. Histologically, healed bone of 8-weeks were embedded with thick and compact osseous pattern and trabecular woven bone of 4-weeks. Also, no significant difference in PeriotestⓇ value of implant could be found between experimental group and control group after placement and on the same day of sacrifice.

CONCLUSION: The result indicates that MyDas Joy-1Ⓡ implant showed a histological bone response similar to ITI-SLAⓇ implant after 4 to 8 weeks. In conclusion, this result suggests that MyDas Joy-1Ⓡ implant can be placed immediately after extraction.