가토 두개관에서 골결손부에 Allomatrix의 공기노출 시간에 따른 골형성 효과 비교

Abstract

Purpose: The purpose of this study is to evaluate the degree of the bone formation when Allomatrix, putty type allograft material, is applied at bone defects formed at rabbit’s calvarium when varying air exposure time.

Materials and Methods: We divided by 4 sectors about 4cm diameter area at calvarium of 6 rabbits and the bone defect area of 8mm diameter and 2mm depth were formed. nothing was appplied at left upper side. each, 3day exposed graft material at right upper side, 1day exposed graft material at right lower side and 1hour exposed graft material at left lower side was applied and set these 8 week group. after 4 weeeks, another 6 rabbits were experimented by same method and set these 4 week group. and rabbits were sacrificed and we made specimens by resin blocks and after, we made specimen sliceds.

Results: Degree of bone formation was evaluated by new bone formation area and there was no statistical significance between each groups by one way ANOVA and p value was 0.75 at 4week group and 0.696 at 8 weeks group.

Conclusions: The degree of bone formation by Putty type allograft material “Allomatrix” exposed to air pollution for various time did show any difference.

Key words: Allograft, Bone graft, Bone regeneration