EMLA 크림이 항생제 피내반응 검사에 미치는 효과

Abstract

Background: The use of a local anesthetic cream composed of a mixture of lidocaine and prilocaine (EMLA 5%) has been considered to relieve the pain of intradermal skin test of antibitotics. As of yet, the effects of the cream in skin tests has been unclear.

Purpose: The purpose of this study was to identify the effects of the EMLA cream on the pain and discomfort in intradermal (ID) skin test, but also skin reaction after the skin test.

Methods: Forty-three nurse-volunteers were skin tested with 0.01 ml - 0.05 ml ampicillin sodium. These were repeated for ID skin test on each forearm, before and after applying EMLA cream with occlusive dressing for one hour. The scores of the pain and discomfort were measured before and after the EMLA cream treatment. The transversal diameter of the wheal and redness was read after 15 minutes after the skin test. The results were compared using a paired t-test.

Results: Pain and discomfort on EMLA cream treatment were significantly lower than that of non-EMLA cream application. There was no difference in skin reaction; reading of the skin test was not affected by EMLA cream.

Conclusions: EMLA cream was found to be an effective local anesthetic to relieve the pain and discomfort of clients in intradermal skin test of antibitotics.

Keywords: Local anesthetics, EMLA, Intradermal tests, Pain