Povidone-Iodnie과 Chlorhexidine 용액의 적용에 따른 타액 내 세균수의 비교

Abstract

It is important to sterilize oral cavity with disinfectants before the dental surgery. The reduction of the oral microflora before the surgery can lower the possibility of infection. Though povidone-iodine (PVI) and chlorhexidine (CHX) are used widely for oral disinfection, clear criteria about their use and application was not established, but have been being used according to clinical experiences of clinician. The purpose of this study is to investigate not only the effects of PVI and CHX on salivary bacterial counts when applied in oral cavity before surgery, but also the preference of subjects and to evaluate the effectiveness and propriety of clinical appliance. The subjects of this study were 20 volunteers aged between 23 to 31 years old, and they didn't have any systemic disease and antibiotics within 3 month. 2.5㎖ of non-stimulus saliva was obtained from every volunteer. In each Group, 2.5㎖ of saliva was gathered PVI was applied for 3 minutes to Group 1 and CHX was applied for 3 minutes to Group 2. Plates which were made from each sample were cultured for 48 hours. Under aerobic circumstance, the number of colony-forming units (CFU) and the percentage of decrement of the CFU to the disinfectant solution were calculated and statistically analyzed. Also, volunteers's over the smell, taste and feeling of the disinfectants were collected through the questionnaires. The CFU measured after disinfections showed significant decrease in both (P<0.01). However, comparison of reduction rate of CFU between two groups did not show any statistical significance (p>0.1). In 20 subjects, preference of CHX was excellent among all three features. And the most of subjects preferred CHX to PVI. Both PVI and CHX proved their effective sterilizing effects. However, two disinfectants showed no statistically significant differences in the reduction rate of salivary bacterial counts.