성견에서 Dentis？？ 임플란트 주위 골 결손부에 이식된 이식재에 따른 골형성에 관한 비교 연구

Abstract

The aim of this study is to compare the bone formation according to the graft materials(autografts, allograft, xenograft) placed into the bone defects around the implant. Four bone defects using 8mm trephine bur were made in both ilium of 4 mongrels then 32 RBM surface implants were placed. No bone graft in bone defects was done in control group. In experimental groups, 3 different bone graft materials were placed in gaps between implant and the bone: Bio-oss？？ for the experimental group 1; TutoplastTM for the experimental group 2; spongeous bone harvested from adult dog's ilium for the experimental group 3. Two adult dogs were sacrificed in 4 and 8 weeks of the experiment respectively and tissue samples were assessed histometrically. In the control group, immature new bone formation appeared in periosteum and endosteum of cortical bone in 4 weeks of the placement and generally satisfactory osseointegration was observed on the interface of new bone and implant. In 8-week group, new bone formation was replaced with mature bone, however, new bone formation in the endosteum was continued and favorable osseointegration in the interface of implant was observed. New bone formation was the highest in the experimental group 3 and the next was in the experimental group 2, and then in the experimental group 1, and then finally in the control group. BIC was the highest in the experimental group 3 and the next was in the experimental group 2, and then in the experimental group 1, and then finally in the control group. Greater amount of new bone formation at 8 week group than 4 week group. This study showed that the autogenous bone is the best grafting material. In addition, human mineralized cancellous bone allograft showed the better new bone formation than xenogenic bone.