천연고분자화합물을 이용한 불소겔이 법랑질 탈회에 미치는 영향

Abstract

ABSTRACT

Effect of fluoride in natural polymer on enamel demineralization Ji Yeoun Kim , D.D.S. Advisor : Prof. Nan-Young Lee D.D.S., M.S.D. Ph. D Department of Dentistry Graduate School of Chosun University

We have developed a sodium fluoride containing gelatin and methyl cellulose gel. Cariostatic abilities of those gel were investigated and compared with APF gel and fluoride varnish(Cavityshield TM). We prepared the bovine tooth samples and divided into two surface, control side and experimental side in same specimen for exclusion of difference between specimens. The experiment was consisted of 4 groups : (I) APF gel : (II) Cavityshield TM : (III) Gelatin F gel : (IV) Methyl cellulose F gel Decalcification were produced by placing each specimen into artificial acidic solution(pH 4.0) for 72 hours. Surface microhardness were measured and depth of demineralization lesion were measured by polarizing light microscope. The results were as follows: 1. The difference of VHN between control and experimental side is smallest in group I (p<0.05). 2. The largest difference was shown in group II (p<0.05). 3. There were no significant difference between group III and IV in microhardness test (p>0.05). 4. The difference of lesion depth is smallest in group I (p<0.05). 5. There were no significant difference between group II, III and IV in lesion depth (p>0.05).

These result indicate that experimentally developed gelatin and methyl cellulose F gel is more effective than APF gel and have a same effect to fluoride varnish.