법랑질 인공우식병소에서 APF gel과 CPP-ACP 제제의 재광화 효과

Abstract

Much work has been carried out using the fluoride ion to prevent and reverse dental caries. It certainly encourages remineralziation and also prevents dental caries. However, the remineraliziation developed by these means is superficial only leaving lower levels of demineralized lesion with a degree of porosity and incomplete mineralization. And we must consider its toxic effects when it is ingested for overdose. The CPP-ACP paste is able to remineralize the incipient lesion and has no harmful effects when it is ingested, because it was made form casein which is from the protein of milk. The purpose of this article is to compare the remineralization effects between APF gel and the CPP-ACP paste. we applicated the APF gel and CPP-ACP paste on the artificial enamel carious lesion. After 14 days, we measured the surface microhardness and observed the remineralized lesion under polarized light microscope.

The results were as follows : 1. The surface microhardness of group III was the highest, followed by group II, and I(p<0.05). 2. The surface microhardness of group III was significantly higher than those of group I, and II(p<0.05). 3. We could observe thin and irregular remineralization layer of group II, and regular and moderate remineralization layer of group III under polirized light microscope.

keywords : CPP-ACP, APF gel, remineralization, microhardness, polarized light microscope