난소종양의 악성과 양성의 감별로 수술전 초음파소견과 종양표지자의 효용성에 대한 연구

Abstract

Of 202 tumors there were 20 malignancies in 61 tumors with a MI≧7 . Stage of disease was as follows: stage I, 25; stage II, 1; stage III, 6; Stage IV,3. A MI score of ≧7 as indicative of malignancy was associated with the following statistical parameters: sensitivity 0.571, specificity 0.754, PPV 0.328, NPV 0.893. MI≧5 as indicative of malignancy was associated with: sensitivity 0.743, specificity 0.293, PPV 0.181, NPV 0.845. Of 202 tumors there were 22 malignancies in 54 tumors with a CA-125 >30 u/ml. A CA-125 of >30 u/ml as indcative of malignancy was associated with the following statistical parameters: sensitivity 0.629, specificity 0.808, PPV 0.407, NPV 0.912. A CA-125 of >27 u/ml27as indicative of malignancy was associated with: sensitivity 0.657, specificity 0.826, PPV 0.442, NPV 0.920. The result is an optimal point 6.5-7.5 in MI, 25.6-28.5 u/ml in CA-125.