성견에서 임플란트 주위염 치료시 이산화탄소 레이저의 효과

Abstract

Numerous applications for dental lasers have been proposed for both clinical use and experimental purpose. A new indication might be the decontamination of exposed implant surface which resulted from peri-implantitis in order to induce re-osseointegration. The purpose of this experimental study was to examine the effect of the decontamination of CO2 laser in treatment of ligature-induced peri-implantitis in dogs. The treatment outcome was evaluated by histomorphometric analysis of the mean percentage of new bone formation within the limit of the 5 most coronal threads which lost bone contact due to peri-implantitis. A total 24 implants with a sandblasted with large-grit and acid-etched (SLA) surface were inserted in six mongrel dogs. After a 3-month healing period, experimental peri-implantitis characterized by a bone loss of about 3mm was established by inducing with wires. And then wires were removed and plaque control was implemented. Surgical treatment involving flap procedure + debridement of implants surface with chlorhexidine and saline (group 1), flap procedure + GBR with absorbable collagen membrane (Bio-Gide) and mineralized bone graft (Bio-Oss) (group 2), and flap procedure + CO2 laser application + GBR (group 3) was performed. The animals were killed 8 weeks and 16 weeks after treatment, respectively. A histomorphometric analysis confirmed statistically considerable new bone formation (80.88 ± 7.72) within the threads in group 3 compared with group 1 (31.63 ± 15.32) at 16 weeks (P<0.05). And intragroup analysis showed considerable increase of new bone formation in group 3 at 16 weeks compared with 8 weeks (P<0.05). The present study demonstrates considerable new bone formation after treatment of experimental peri-implantitis with flap procedure, CO2 laser application and GBR.