CHOSUN

Effect of Mycoplasma pneumoniae Infection on N-terminal Pro-brain Natriuretic Peptide Level in Patients with Kawasaki Disease

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Author(s)
Young Min Jo Seung Hyun Lee Cheol Hwan So Chang Woo Lee Du Young Choi Seung Taek Yu
Issued Date
2018
Keyword
Kawasaki disease Mycoplasma pneumoniae N-terminal pro-brain natriuretic peptide Coronary artery disease Heart aneurysm
Abstract
Coronary artery complications are the most severe complications in Kawasaki disease (KD). Its cause is unclear but superan-tigens are considered to influence KD. This study aimed to determine whether coronary artery complications and level of N-terminal pro-brain natriuretic peptide (NT-proBNP) are associated with Mycoplasma pneumoniae (MP) in patients with KD. We studied 142 pediatric patients diagnosed with KD. MP immunoglobulin M (IgM) antibody examination was conducted. All patients underwent echocardiography, and coronary artery dilatation was defined as a coronary Z-score >2.0. We also evaluated their NT-proBNP findings. The independent t-test and Pearson chi-squared test were used to analyze between-group differences; a p-value <0.05 was considered statistically significant. Forty children were MP IgM positive. MP IgM-positive patients were older than MP IgM-negative patients. There was no significant difference in the clinical manifestations between the groups. Comparison of the mean Z-score of the coronary artery revealed that only the Z-score of the left anterior descending artery was significantly different between the groups. However, the number of patients with coronary artery dila-tation was not significantly different between the groups. Our findings demonstrated no relationship between MP infection and coronary artery dilatation or NT-proBNP levels in patients with KD.
Publisher
조선대학교 의학연구원
Citation
Young Min Jo. (2018). Effect of Mycoplasma pneumoniae Infection on N-terminal Pro-brain Natriuretic Peptide Level in Patients with Kawasaki Disease, MJCU | Vol.43, No.2 p.109 ~ p.113
Type
Laboratory article
ISSN
1225-0082
URI
https://oak.chosun.ac.kr/handle/2020.oak/17201
http://www.chosun.ac.kr/user/indexSub.do?codyMenuSeq=497586153&amp;siteId=medres
Appears in Collections:
2018 > Vol.43, No.2
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