기능성 식품개발과 효능검사

Abstract

Nowadays the sharp rise of obesity, diabetes and cancer patients owing to the change of dietary habits has been one of the serious problems in 21th century. Thus in this study functional foods by the correct choice of functional stuff have been developed based on the change of this dietary environment. And this study aims to see what effect these functional foods have on weight, blood glucose levels and anticancer. In this point of view, in the study were conducted animal tests of 21-gram male ICR mice, which were used by three per test in the experimental group and the comparison group. In the study were measured weight loss and anticancer effect from soybean tofu and green tea tofu, weight loss effect and change of blood glucose levels from soybean milk and onion soybean milk, anticancer effect from ordinary feed stuff and oriental medicine functional food and change of blood glucose levels from common ramyon and potato ramyon under the same condition.

The findings were as follows: First, pre-treated extract of soybean tofu and green tea tofu was treated to 21-gram male ICR mice in oral dosage three times a day in fixed-dose at fixed-time, and the result of measuring the weight every two days over five rounds was that the experimental group (green tea tofu mice) showed more significant weight loss effect than the comparison group(soybean tofu mice). Also the result of measuring cancer preventive effect as to concentration levels by MTT assay was that the experimental group(green tea tofu mice) showed more significant anticancer effect than the comparison group(soybean tofu mice). Second, pre-treated extract of soybean milk and onion soybean milk was treated to 21-gram male ICR mice in oral dosage three times a day in fixed-dose at fixed-time, and the result of measuring the weight every two days over five rounds was that the experimental group(onion soybean milk) showed more significant weight loss effects than the comparison group(soybean milk). And the result of measuring blood glucose as to concentration levels was that the onion soybean milk mice showed more significant blood glucose reduction effect than the blood glucose reduction effect than the comparison group(soybean milk mice) Third, pre-treated extract of ordinary feed stuff and oriental medicine functional raw food was treated to cultured cancer cell strains, and the experiment for cancer preventive effect as to concentration levels by Heochst 33342 and MTT assay showed the experimental group (oriental medicine functional food) showed more significant anticancer effect than the comparison group(ordinary feed stuff) Fourth, pre-treated extract of common ramyon and potato ramyon was treated to 21-gram male ICR mice in oral dosage three times a day in fixed-dose at fixed-time and the result of measuring the blood glucose levels every two days over five rounds was that the experimental group(potato ramyon) showed significant blood glucose decrease effect than the comparison group(common ramyon). Therefore, It can be concluded that green tea tofu has weight loss and anticancer effect, onion soybean milk has weight loss and blood glucose decrease effect, oriental medicine functional food has anticancer effect and potato ramyon has blood glucose decrease effect. Their prospects as the future functional foods will be promising because green tea tofu, onion soybean milk, oriental medicine functional food using yeast and potato ramyon have been developed in this study, and this study identified their effects on the weight loss, blood glucose decrease and anticancer. Thus the functional foods which have been developed in this study can be considered as a precautionary indicator against adult diseases.

Key words: Green tea, Onion soybean milk, ICR mice, Cancer, Oriental medicine functional food, potato ramyon