성견에서 2급 이개부결손부 치료시 자가치아골이식재의 효과 : 조직학적 및 조직형태계측학적 연구

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The purpose of this study was to evaluate the efficiency of combined use of autogenous tooth bone graft (Auto-BTⓇ) with Polytetrafluoroethylene (PTFE) membrane for surgically created Class Ⅱ furcation defects histologically and histomorphometrically.
Five dogs were used in this study. The Class Ⅱ furcation defects (5 x 4 x 3 mm) were formed at lower third and fourth premolar, respectively. The control group defects were covered with PTFE membrane only while the experimental group defects were treated with Auto-BTⓇ and then covered with PTFE membrane. The healing patterns were observed at 4 weeks and 8 weeks after treatment. Mesio-distal sections were obtained and stained with hematoxylin and eosin. Histoloic and histomorphometric analyses were performed. Statistical analyses were performed using Mann-Whitney test and Wilcoxon ranked test.
The formation of new bone, cementum, and periodontal ligament were similar in both groups. Regeneration of bone and connective tissue in the furcation defects were almost complete in most of the experimental specimens. There were no statistically significant differences between groups for histomorphometric measurements.
In conclusion, this study showed that Auto-BTⓇ graft revealed favorable effect on the healing of Class II furcation defects, but there were no statistically significant difference between the two groups: PTFE membrane with Auto-BTⓇ or PTFE membrane only.

Keyword: Furcation defects; guided tissue regeneration; polytetrafluoroethylene;
autogenous tooth bone graft.
Alternative Title
Effect of autogenous tooth bone graft on Class II furcation defects in dogs : A histologic and histomorphometric study
Alternative Author(s)
Cho Ah-Young
조선대학교 대학원
일반대학원 치의학과
김 병 옥
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Table Of Contents
I. 서 론 1
II. 실험 재료 및 방법 3
1. 실험 재료 3
2. 실험 방법 3
(1) 동물 준비 3
(2) 수술 방법 3
3. 조직학적 평가 및 조직 계측학적 평가 5
(1) 조직학적 평가 5
(2) 조직계측학적 평가 5
4. 통계학적 분석 6
III. 연구 결과 7
1. 임상적인 관찰 7
2. 조직학적 분석 7
(1) 4주군 7
(2) 8주군 8
3.조직계측학적 분석 9
IV. 총괄 및 고찰 12
참고문헌 16
조선대학교 대학원
조아영. (2013). 성견에서 2급 이개부결손부 치료시 자가치아골이식재의 효과 : 조직학적 및 조직형태계측학적 연구.
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General Graduate School > 4. Theses(Ph.D)
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