성견에서 2급 이개부결손부 치료시 자가치아골이식재의 효과 : 조직학적 및 조직형태계측학적 연구

Abstract

The purpose of this study was to evaluate the efficiency of combined use of autogenous tooth bone graft (Auto-BTⓇ) with Polytetrafluoroethylene (PTFE) membrane for surgically created Class Ⅱ furcation defects histologically and histomorphometrically. Five dogs were used in this study. The Class Ⅱ furcation defects (5 x 4 x 3 mm) were formed at lower third and fourth premolar, respectively. The control group defects were covered with PTFE membrane only while the experimental group defects were treated with Auto-BTⓇ and then covered with PTFE membrane. The healing patterns were observed at 4 weeks and 8 weeks after treatment. Mesio-distal sections were obtained and stained with hematoxylin and eosin. Histoloic and histomorphometric analyses were performed. Statistical analyses were performed using Mann-Whitney test and Wilcoxon ranked test. The formation of new bone, cementum, and periodontal ligament were similar in both groups. Regeneration of bone and connective tissue in the furcation defects were almost complete in most of the experimental specimens. There were no statistically significant differences between groups for histomorphometric measurements. In conclusion, this study showed that Auto-BTⓇ graft revealed favorable effect on the healing of Class II furcation defects, but there were no statistically significant difference between the two groups: PTFE membrane with Auto-BTⓇ or PTFE membrane only.

Keyword: Furcation defects; guided tissue regeneration; polytetrafluoroethylene; autogenous tooth bone graft.