연속적인 프로칼시토닌 검사 결과의 변화 형태 분석

Abstract

The blood culture the usability of PCT is evaluated the result between CRP (C-reative protein), that is the indicator who is well the blood culture result and PCT known to the existing, is compared the procalcitonin(PCT) is the indicator of the diagnosis of the inflammation and sepsis. The PCT and CRP was compared in five categories of PCT against 205 patients. And the additional analysis the blood culture test was done in 158 patients. ThePCT analyzed the electrochemical luminescent immunoassay (ECLIA) to the immunoassay equipment cobas e . The CRP measured with the scattering method (nephelometer, SIEMENS Co, Germany) in the Behring Nephelometer II equipment. The mean concentrations of CRP in five categories of PCT were 3.03 mg/dL, 6.59mg/dL, 11.26mg/dL , 15.45mg/dL , 17.38mg/dL , respectively(P<0.001). Both PCT and CRP showed significant differences between the two positive and negative groups of blood culture(PCT, 6.83ng/mL, 3.91ng/mL, P=0.07; CRP, 10.44mg/dL, 9.11mg/dL, P=0.012). The diagnostic utility of PCT is superior to that of CRP for the patients with blood culture-positive sepsis. PCT seems to be reliable for sepsis diagnosis, and the change trend of PCT will be able to provide the useful clinical information for the serious patient treatment.