티타늄 표면의 반응기가 조골모세포 증식에 미치는 영향

Abstract

Titanium (Ti) have been widely used as biomaterials due to electrical and thermal conductivity and mechanical properties. To improve the biocompatibility, several surface treatment methods were suggested. Among the surface treatment, plasma surface modification can be used to improve the surface properties of commercial pure titanium. The purpose of this study was to investigate of optimum conditions of plasma polymerization process and evaluate the proliferation of osteoblast like cell (MC3T3-E1). Titanium surface modification was carried out by depositing an thin polymeric layer containing carboxyl, amine and hydroxyl groups through plasma polymerization using an acrylic acid (AA), allyl amine and allyl alcohol monomer. The chemical structure and morphology of polymeric thin films were investigated by X-ray photoelectron spectroscopy (XPS), fourier transform infrared (FTIR), and scanning electron microscopy (SEM). Hydrophilic property was measured by contact angle. The content of carboxyl and amine group were measured by TBO and MO assay. The plasma polymerized polymeric thin films were identified by FTIR and XPS. Surface modified Ti surface showed good proliferation of MC3T3-E1 than that of untreated Ti surface.