비파잎 에탄올 추출물이 고지방-고콜레스테롤 식이를 급여한 흰쥐의 지질대사 및 항산화 활성에 미치는 영향

Abstract

This study was carried out to investigate the effects of Eriobotrya japonoca Lindl.(Loquat) leaf ethanol extract on lipid metabolism of serum, liver and adipose tissue, and anti-obesity effect in rats fed a high fat-high cholesterol diet for 4 weeks. It was also conducted to investigate major chemical components analysises of loquat leaf. The proximate compositions of loquat leaf as a dry matter basis were 8.78% of moisture content, 6.74% of crude protein, 7.87% of crude fat, 6.99% of crude ash, 43.61% of dietary fiber and 26.01% of carbohydrate, respectively. Analysing free amino acids, 16 kinds of components total amino acids, 17 kinds of components were isolated from loquat. The essential amino acid contained in loquat leaf accounted for 50.15% of total amino acid, while the non-essential amino acid accounted for 49.85%. Analysing total fatty acids, only 5 kinds of lauric acid, myristic acid, pentadecanoic acid, stearic acid and oleic acid were detected. The contents of vitamin A, vitamin E and vitamin C were 0.039 mg%, 0.096 mg% and 0.575 mg%, respectively. The mineral contents of loquat leaf were greater in order of Zn