농촌지역 주민의 공복혈당장애 유병률과 관련요인

Abstract

This study was performed to investigate the prevalence of impaired fasting glucose (IFG) and its related characteristics among healthy adults in some Korean rural area. We conducted a cross-sectional study using data from 1352 adults over age 40 and under age 70 and free of diabetes mellitus (DM), cardiovascular diseases (CVD) and other diseases and participated in a survey conducted as part of the Korean Rural Genomic Cohort Study(KRGCS). IFG was defined as a serum fasting glucose level between 100 and 125 mg/dl. The prevalence of IFG was 20.4% in men, 12.7% in women and 15.5% overall. Multivariate logistic regression analyses demonstrated that the independent risk factors of IFG were male, having a family history of DM, quartiles of gamma glutamyltransferase and high sensitive C-reactive protein and waist circumferences. Homeostatis model assessment-insulin resistance (HOMA-IR) was very strongly associated with IFG. The prevalence of metabolic syndrome (MS) and MS components was higher in IFG then in normal fasting glucose (NFG). In conclusion, this result of study could be supplied the evidence to find the high risk population and to think out a strategy for IFG. Further research is needed to explain the causal relationship and mechanism of IFG.