안트라피라졸 고분자의 합성 및 형과 특성

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Activation of the JNK pathway has been documented in a number of disease setting, providing the rationale for targeting this pathway for discovery.
In addition, molecular genetic approaches have validated the pathogenic role of this pathway in several diseases.
Anthrapyrazolone compounds have been used as a drug for treatment of the disease relating to the Jun N-terminal Kinase pathway such as autoimmune and inflammatory disease. They include rheumatoid arthritis, asthma, inflammatory, bowel disease, multiple sclerosis, cardiovascular disease etc.
The Jun N-terminal Kinase(JNK) pathway is activated by exposure of cells to
environmental stress or by treatment of cells with pro-inflammatory cytokines. argets of the jnk pathway include the transcription factors c-jun and ATF2. hese transcription factors are members of the basic leucine zipper group that
bind as homo and hetro-dimeric complexes to AP-1 and AP-1-like sites in the promoters of many genes.
In this study the polymerization of anthrapyrazolone-containing monomer is proposed to reduce the toxicity of the drug. also its luminescence characteristics has beech studied since it has conjugated structure and large cross section of chromophore.
Alternative Author(s)
Kee seung-beom
일반대학원 공과대학
일반대학원 고분자공학과
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Table Of Contents
제 1 장 서 론 1
제1절 JNK(c-Jun N-terminal kinase) 소개 1
제2절 전기 발광 디스플레이 등장 2
제3절 유기EL(Organic Electroluminescence) 4
제4절 유기 전계 발광소자(organic light-emitting diode) 6
제5절 유기 전계 발광소자(organic light-emitting diode)
의 mechanism 과 재료 9
1. 전기 발광 원리 9
2. 발광 재료 12
3. OLED 기술동향 과 활용분야 13

제 2 장 실 험 15
제1절 시약 및 기기 15
제2절 단위체의 합성 16
제3절 중합체의 합성 37
제 3 장 결과 및 고찰 41
제1절 단위체 및 중합체 합성 확인 41
제2절 단위체 및 중합체 특성 확인44
1. 단위체 및 중합체의 일반적인성질44
2. 중합체의 형광특성46
제3절 결론 51

조선대학교 일반대학원
기승범. (2007). 안트라피라졸 고분자의 합성 및 형과 특성.
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