젊은층 위암 환자들의 임상병리학적 특성

Abstract

Purpose: The aim of this study was to analyze the clinicopathological characteristics related to gastric cancer in the young aged patients. Materials and Methods: A total of 22 patients with gastric cancer under 35 years old treated at Chosun University Hospital from Jan 1996 to June 2002 were enrolled in this study. The clinicopathological features were investigated by analyzing medical records and survival rate was evaluated by long-term follow-up. Results: Of the 566 patients, 22(3.88%) were in the young age group. The male-to-female ratio was 1.44:1. Three patients(13.6%) had a family history of gastric cancer. The microscopic findings showed 10 poorly differentiated adenocarcinomas(45.5%) and also 10 signet ring cell carcinomas(45.5%). Diffuse type by Lauren classifications was 11(50.0%). Disease-specific 5 year survival rate of the patients with the tumor size below 2cm was 92.3%. The radical surgery by standard D2 resection was done for 19 patients, with the radical cure control ratio of 86.4%. Anticancer chemotherapy was administered for the patient more than stage 2. 5 year survival rate of stage 1 gastric cancer was 100%. Conclusion: The clinicopathological differences of the young aged patients with gastric cancer were high incidence of poorly differentiated type and high survival rate of early stage cancer. Key words: gastric cancer, young, clinopathological feature