일반인과 비만인의 UCP 2 유전자 다형성, 식습관, 비만도 및 체성분의 비교 연구

Abstract

This study was carried out to compared the characteristics of the normal university students with those of obesity university students. The survey was carried out by peripheral blood sampling and self-questionnaires with 126 normal and 60 obesity university students. The results are summarized as follows. Breakfast was skipped in 43.7% of normal and 49.3% of obesity students and it appeared obese students eat faster than normal students. The percentage of weight control experience were 49.2 and 71.0 in the normal and obese students, respectively. Blood levels of lipid profiles(triglyceride, LDL cholesterol, and HDL cholesterol), hemoglobin, AST and ALT were anaylzed. In UCP2 genes, the frequency of deletion homozygote(DD) was 71.5%, heterozygote(DI) was 26.9% and insertion homozygote(II) was 1.6%. Plasma levels of triglyceride, total cholesterol, LDL cholesterol, and HDL cholesterol of normal students were 79.06, 172.25, 100.86 and 57.03mg/dl, and those of obese students were 93.06, 173.22, 101.22 and 54.39mg/dl, respectively. Blood parameters were in normal range in both group. Plasma triglyceride, total cholesterol and LDL cholesterol levels of obese students were higher than those of normal students. On the other hand, plasma HDL cholesterol levels of obese students were lower than those of normal students. Plasma levels of AST and ALT were in normal range in both group. However, AST and ALT levels of obese students were higher than that of normal students. Therefore they should have a nutritional education program to improve their dietary and living habits for obese students' health. And nutritional education program should be organized practically and systematically.