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복막투석 환자에서 혈청 N-terminal pro-Brain Natriuretic Peptide와 세포외액과 좌심실부전간의 연관관계에 관한 연구

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Author(s)
윤나라
Issued Date
2006
Abstract
Background
This study inquired the relationship between serum N-terminal pro-brain natriuretic peptide(NT-pro BNP) levels and extracellular water(ECW%) and left ventricular(LV) dysfunction in continuous ambulatory peritoneal dialysis (CAPD) patients.
Method
We conducted a prospective study of 30 CAPD patients : 19 males, 11 females: mean age 47±12 years; 14 with diabetes mellitus and 16 non-diabetes mellitus. Each patient was admitted to Department of internal medicine, Chosun University Hospital between Febrary, 2006 and Octorber, 2006. Echocardiography was performed using a HDI 5000(Philips,USA), allowing M-mode,two-dimensional measurement. A multifrequency bioimpedance analyzer was used; ECW% was calculated as a percentage of total body water and was understood the index of volume load of CAPD patients.
Result
Mean serum NT-pro BNP level was 14236.56(83-35000)pg/mL.. LV mass index and LV ejection fraction (%) were 151.67±42.5g/m², 57.48±12.9%. Mean Extracellular water(%) was 35.97±1.04%. Serum NT-pro BNP levels correlated positively with LV mass index (r=0.768, p=0.01), and Extracellular water (%)(r=0.866, p=0.01) and negatively with LV ejection fraction (r=-0.808, p=0.01.)
Conclusion
Serum NT-pro BNP levels significantly correlated with LV mass index,LV ejection fraction and extracellular water(%). Therefore, serum NT-pro BNP levels can be clinical predictive maker for LV hypertrophy, LV dysfunction and hydration status in CAPD patients.
Alternative Title
Relationship between serum N-terminal pro-brain natriuretic peptide density and Left ventricular dysfunction and Extracellular water in continuous ambulatory peritoneal dialysis patients
Alternative Author(s)
Yun, Na Ra
Affiliation
조선대학교 대학원
Department
일반대학원 의학과
Advisor
정종훈
Awarded Date
2007-02
Table Of Contents
表目次 = 2
圖目次 = 3
ABSTRACT = 4
I. 序論 = 6
II. 硏究對象 및 方法 = 7
III. 結果 = 9
IV. 考察 = 11
V. 結論 = 14
Ⅵ. 要約 = 15
參考文獻 = 21
Degree
Master
Publisher
조선대학교 대학원
Citation
윤나라. (2006). 복막투석 환자에서 혈청 N-terminal pro-Brain Natriuretic Peptide와 세포외액과 좌심실부전간의 연관관계에 관한 연구.
Type
Dissertation
URI
https://oak.chosun.ac.kr/handle/2020.oak/6625
http://chosun.dcollection.net/common/orgView/200000234034
Appears in Collections:
General Graduate School > 3. Theses(Master)
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