당뇨병 환자에서 백내장 유병률에 대한 고찰

Abstract

Purpose : This study was performed to evaluate the prevalence and risk factors for cataracts in patients with diabetes mellitus quantitatively in Korean patients. Methods : One thousand and seventy four patients(male : 410, mean age : 59.18 ± 10.94 years) with diabetes who was performed ophthalmologic evaluation was studied retrospectively. Risk factors like sex, age, age at diagnosis, duration of diabetes, fasting blood sugar, HbA1c, BUN, creatinine, total cholesterol etc were compared between patients with cataract and without cataract. Results : Five hundred and eighty patients(54.00%) had cataract at evaluation. Female was more common in cataract group than the control group. The mean age, and mean age of the first diagnosis of diabetes mellitus were older in cataract group than control group. HbA1c, total cholesterol, triglyceride and LDL-cholesterol were not different between two groups. Duration of diabetes was significantly longer in patients in cataract group than control group(11.56 ± 7.58 years vs. 7.48 ± 6.20 years, p < 0.001). The patients in cataract also had higher level of BUN, creatinine, and fasting blood sugar than those control group. Multiple regression analysis revealed that the duration of diabetes(p < 0.001) and BUN(p = 0.016) were significantly correlated with the cataract. Conclusions : The duration of diabetes was the significant risk factor of cataract in patients with diabetes. This finding indicates the accumulated effect of hyperglycemia is related to the lens transparency in patients with diabetes.