녹차 polyphenol의 전분소화억제효과

Metadata Downloads
Issued Date
polyphenols|blood glucose level|hypoglycemic effect
Background : Many studies suggested that a green tea extraction have antidiabetic effect. Hara et al. reported that tea catechin inhibit alpha-amylase activity in the small intestine. Alpha-amylase cleaves starch to maltose and elevates blood glucose level.
Purpose: In this study, Inhibitory effects of polyphenol on digestion of starch and its hypoglycemic effects were studied.
Methods: Extraction was isolated from green tea and analyzed. Splague-Dowley rats were randomly devided and 6 studies were performed.: Starch, maltose, glucose and extraction mixed things load tests were performed and were compared with control group by serum glucose level. Alloxan diabetic rats were devided into two groups. Control group and experimental group administered polyphenol mixed food were compared by serum glucose level. We also studied hepatic and renal toxic effect of polyphenols.
Results: Serum glucose levels were reduced only in the group administered starch plus polyphenol. Serum glucose levels of other groups were increased. In alloxan diabetic rats, glucose levels of experimental group were reduced significantly compared with control group. Polyphenol had not acute toxic effect on liver and kidney.
Conclusion: Polyphenol from green tea blocked process from starch to maltose, and had hypoglycemic effect. From this results, we suggested that polyphenol may be used for hypoglycemic agent safely and effectively.
Alternative Title
Inhibitory effect of green tea polyphenol on digestion of starch
Alternative Author(s)
Lee, Beom-Ju
조선대학교 대학원
일반대학원 의학과
Awarded Date
Table Of Contents
Ⅰ. 서론 = 5
Ⅱ. 실험재료 및 방법 = 7
A. 실험 대상 = 7
B. 녹차 추출물의 제조 = 7
C. 녹차 추출물의 성분분석 = 7
D. 녹차추출물의 전분 소화, 흡수 억제 실험 = 7
1. 전분 부하실험 = 8
2. 맥아당 부하실험 = 8
3. 포도당 부하실험 = 8
E. 당뇨병 흰쥐에서 녹차추출물의 혈당강하 작용 = 9
F. 녹차 추출물의 간 및 신장독성시험 = 9
G. 결과 분석 = 9
Ⅲ. 실험결과 = 10
A. 녹차 추출물의 성분 분석결과 = 10
B. 전분의 소화 흡수에서 녹차 추출물이 혈당에 미치는 영향 = 10
C. 맥아당의 소화 흡수에서 녹차 추출물이 혈당에 미치는 영향 = 10
D. 포도당의 소화 흡수에서 녹차 추출물이 혈당에 미치는 영향 = 11
E. 당뇨병 흰쥐에서 녹차추출물의 혈당강하 작용 = 11
F. 녹차 추출물의 간 및 신장독성시험 = 11
Ⅳ. 고찰 = 18
Ⅴ. 요약 및 결론 = 20
참고문헌 = 23
조선대학교 대학원
이범주. (2004). 녹차 polyphenol의 전분소화억제효과.
Appears in Collections:
General Graduate School > 3. Theses(Master)
Authorize & License
  • AuthorizeOpen
  • Embargo2005-11-12
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.