악성 늑막 삼출액에서 Viscum album의 치료

Abstract

Background. Malignant pleural effusion are a common clinical problem in neoplastic patients. With the diagnosis of a malignant pleural effusion, palliative therapy was done. The one of treatment was a chemical pleurodesis. Talc was most commonly used a scleroing agent, but the quality of patient life was not improved. We was evaluated by other agent, Viscum album for relief of malignatnt pleural effusion Methods. From November 2001 to October 2003, 17 patients who underwent to chemical pleurodesis on the malignant pleural effusion. We compared with talc(group Ⅰ : 10 patients) and Viscum album(group Ⅱ : 7 patients). We analysed them retrospectively in term of various factor and results. Results. There were signigicant differences between group Ⅰ and group Ⅱ in the sex ratio, mean age, origin of primary cancer and site, but, group Ⅰ was better than group Ⅱ in the successful rate(80%:71%) and length of chest tube stay. Group Ⅱ was better than group Ⅰ in the Karnofsky performance and recurrence. The failed treatement group was related to the pleural fluid pH and interval of initial chemical pleurodesis after thoracostomy. Conclusions. Although the chemical pleurodesis with Viscum album was slightly lower than talc in the successful rate, there was an alternative method instead of the chemical pleurodesis with talc to improve the quality of patient's life in malignant pleural effusion.