국내 3차병원에서 급성관상동맥 증후군 후에 퇴원처방약 패턴 및 관찰평가 분석

Metadata Downloads
Issued Date
Acute Coronary Syndrome (ACS) is one of cardiovascular diseases which are mainly caused by atherosclerotic plaque erosion and subsequent coronary thrombus formation. ACS is classified into three types: unstable angina (UA), non-ST elevated myocardial infarction (NSTEMI), and ST-elevated myocardial infarction (STEMI). According to 2014 AHA/ACC guideline, it is strongly recommended that aspirin ± clopidogrel, ACE-I/ARB, β-blocker, and statin should be prescribed to ACS patients discharged in order to prevent secondary ACS. The aims of this study were to analyze the prescription patterns of discharge medications after ACS and to perform follow-up evaluation. This study was retrospectively conducted through electronic medical record (EMR) which contained laboratory data and discharge medication lists for ACS patients in a tertiary hospital between September 2009 and August 2013. Out of 1,465 patients during the study period, 494 were selected based on inclusion and exclusion criteria of this study. At discharge, the patients who received the five recommended medications were 374 (75.71%), but the number of these patients remaining on this treatment 12 and 18 months after discharge were 169 (34.21%) and 105 (21.26%), respectively. Enoxaparin, an antithrombotic agent for the reduction of mortality and morbidity of ACS, was prescribed to 352 (71.40%) ACS patients right after admission. Of them, UA, NSTEMI, and STEMI patients were 173 (35.09%), 58 (11.76%), and 121 (24.54%), respectively. Troponin-T (TnT) is used as a biomarker for myocardial injury. hs-Troponin-T (hs-TnT) that is more sensitive than TnT has been measured for ACS patients in this hospital since November 2011. Further studies related to the association of the prevention for secondary ACS with using the strongly recommended discharge medications and follow-up clinical laboratory levels are needed to better optimize the treatment for ACS patients. In addition, the further follow-up evaluation studies regarding ACS medication patterns after 18 months should be conducted.
Alternative Title
Discharge Medication Patterns and Follow-up Evaluation After Acute Coronary Syndrome in a Tertiary Hospital
Alternative Author(s)
Hee Ja Byeon
임상약학대학원 임상약학과
Awarded Date
Table Of Contents

제1장 서론 1
제1절 연구배경 및 연구목적 1
제2장 연구방법 5
1. 연구 대상 5
2. 연구 범위 5
3. 연구 방법 6
4. 통계 방법 7
제3장 연구결과 9
1. 연구 대상에 대한 기본 배경 9
2. ACS 환자에서 퇴원약물 패턴 분석 및 적절성 11
3. 입원, 퇴원 전후 임상 수치 및 관찰평가 25
제4장 고찰 및 결론 52

참고문헌 55
변희자. (2015). 국내 3차병원에서 급성관상동맥 증후군 후에 퇴원처방약 패턴 및 관찰평가 분석.
Appears in Collections:
Medicine & Parmacy > 3. Theses(Master)
Authorize & License
  • AuthorizeOpen
  • Embargo2015-08-25
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.