국내산 개똥쑥 소수성 분획물의 항산회 활성 및 항주름 효과 탐색

Abstract

Artemisia annua belongs to the plant family of Asteraceae and is an annual short-day plant. This plant is known for its various effects such as its anti-cancer, anti-antioxidant, anti-inflammatory, and cardiovascular disease therapies. However, the anti-wrinkle effect of the hydrophobic fraction extract has not been reported yet. In this study, the antioxidant activity and anti-wrinkle activity of the number of hydrophobic fractions of domestic Artemisia annua L is investigated. Three solvent extracts (hot water, 70% ethanol, and 100% methanol) of Artemisia annua L are prepared. In the evaluation results of Artemisia annua L. leaf, antioxidant and anti-wrinkle activities are uncovered. The 100% methanol extract shows the highest antioxidant activities and total phenolic and total flavonoid contents among them. Collagenase inhibition, ellstase inhibition, and hyaluronidase inhibition IC50 rate are 124, 200, and 324 ug/mL, respectively. Therefore, this plant would be a useful anti-wrinkle cosmetic material.