Future perspective of new tooth creation

Abstract

Currently, outcomes of dental stem cells studies indicate that the tooth is an available source for clinical application. Finding a universal cell that can morph into many several types of oral tissues is a key for new tooth creation. If dental stem cells are isolated to form new tooth buds, with creation of an imitative condition to the embryonic jaw, this will be a revolutionary new way to replace a missing tooth. Although investigators have created tooth-like structures in studies, so far, later dental stem cells investigations will be able to create a workable vascularized implant in the human body. This review study discusses current challenges in creating a biological environment that mimics the condition of teeth as they form in an embryo.