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Effect of Solanum Melongena Extract on the Xanthine Oxidase Inhibitory, Nitrite Scavenging, and Angiotensin I-Converting Enzyme Inhibitory Activities

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Author(s)
Hee-Kyung Lee Hyun-Sook Choi Ki-An Cho On-You Choi Ha-Young Koh Ran Kim Du-Bok Choi
Issued Date
2017
Keyword
S. melongena xanthine oxidase inhibitory activity angiotensin I-converting enzyme inhibitory activity nitrite scavenging activity.
Abstract
This research was to study effect of Solanum melongena extract on the xanthine oxidase (XO) inhibitory, nitrite scavenging (NC), and angiotensin I-converting enzyme (ACE) inhibitory activities. All the extracts inhibited the XO and ACE activities in a dose dependent manner. Especially, among various extracts, when 6.0 mg/mL of acetone extract was used, the maximum activity of XO inhibitory was obtained, 65.2%. On the other hand, in the case of methanol and ethanol extracts, they ranged of 61.5 to 62.4%. Acetone extract had a high phenolics and flavonoid concentration compared to other extraxts. Maximum NC activity using hot water extract at pH 1.2 was occurred, 68.7%. ACE inhibitory activity was significantly different among the various extracts at 6.0 mg/mL, values ranged from 35.26 to 56.7%. Especially, when 6.0 mg/mL of methanol and ethanol extracts were used, the highest ACE inhibitory activities were obtained, 57.3 and 56.7%, respectively. These results suggest that XO inhibitory, NC, and ACE inhibitory activities of S. melongena extract were strongly affected by extractant.
Publisher
조선대학교 공학기술연구원
Citation
Hee-Kyung Lee. (2017). Effect of Solanum Melongena Extract on the Xanthine Oxidase Inhibitory, Nitrite Scavenging, and Angiotensin I-Converting Enzyme Inhibitory Activities, 공학기술논문지 | Vol.10, No.1 p.23 ~ p.27
Type
Laboratory article
ISSN
2005-3142
URI
https://oak.chosun.ac.kr/handle/2020.oak/17565
http://www.chosun.ac.kr/user/indexSub.do?codyMenuSeq=23376167&siteId=riet&dum=dum&boardId=168878&page=14&command=view&boardSeq=233135&chkBoxSeq=&categoryId=&categoryDepth=&search=&column=null&searchDate1=&searchDate2=&selColumn=&myList=
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2017 > Vol.10, No.1
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