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발풀고사리 물 추출물의 항산화 및 항암 활성 연구

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Author(s)
조유진 김현우 백효은 김현석 조건웅 박세이 오찬진 오득실 김진
Issued Date
2020
Keyword
Dicranopteris pedeta aqueous extract antioxidant anticancer
Abstract
Ten species belonging to the genus Dicranopteris are distributed throughout the world and Dicranopteris pedeta (Houtt.) Nakaike is distributed in Korea. In this study, the antioxidant and anticancer activities of Dicranopteris pedeta aqueous extract was explored. Antioxidant activity of Dicranopteris pedeta aqueous extract was revealed with a range of 38% to 74% in the DPPH radicals test. The total polyphenols and flavonoids contents of aqueous extract were 92.5 ± 8.68 mg GAE/g and 28.04 ± 4.08 mg QE/g, respectively. Protocatechuic acid, gentisic acid, rutin, vanillic acid, hesperidin, oxyresveratrol, quercetin, and naringenin were detected by HPLC. Cytotoxicity test was conducted using MTT assay in normal cells 293T, cancer cells of YD-10B and HeLa. In the cytotoxicity test, aqueous extract did not show toxicity to normal cells but inhibited cancer cell proliferation. These results suggest that aqueous extracts of Dicroanopteris pedeta could potentially be developed as a functional cosmetics or anticancer agents.
Alternative Title
A study on the antioxidant and anticancer activities of Dicranopteris pedeta aqueous extract
Alternative Author(s)
Eugene Cho Hyoun-Woo Kim Hyo-Eun Baek Hyeon-Seok Kim Geon-Ung Jo Se-I Park Chan-Jin Oh Deuk-Sil Oh Jin Kim
Publisher
조선대학교 공학기술연구원
Citation
조유진. (2020). 발풀고사리 물 추출물의 항산화 및 항암 활성 연구, 공학기술논문지 | Vol.13, No.1 p.39 ~ p.44
Type
Laboratory article
ISSN
2005-3142
URI
http://oak.chosun.ac.kr/handle/2020.oak/16359
https://www.chosun.ac.kr/user/indexSub.do?codyMenuSeq=23376167&siteId=riet&dum=dum&boardId=168878&page=2&command=view&boardSeq=315814&chkBoxSeq=&categoryId=&categoryDepth=&search=&column=null&searchDate1=&searchDate2=&selColumn=&myList=
Appears in Collections:
2020 > Vol.13, No.1
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