Silver Diamine Fluoride(SDF)의 시간경과에 따른 법랑질 탈회억제 효과

Abstract

This study was conducted to compare the demineralization resistance of silver diamine fluoride (SDF) and fluoride varnish after application to sound teeth. 105 specimens composed of incisors of healthy cow were classified as control, fluoride varnish, and SDF groups. Each group was demineralized in seven sections: 24 hours, 72 hours, 7 days, 14 days and 21 days. Subsequently, micro CT analysis was performed to measure the density change of the enamel surface. The density change was measured at three depths by 20um units to analyze the differences in depth. In order to evaluate the total demineralization, the volume of demineralized zone was measured using a 3D image obtained by micro CT. The morphology of the enamel surface was observed using a scanning electron microscope (SEM). In the control group and the fluoride varnish group, the surface density of enamel decreased continuously as the time of demineralization increased. In the SDF group, the density was increased until the 7th day of demineralization and decreased thereafter. However, the decrease was less in the SDF group than in the other groups (p<0.05). In the volumetric change measurement, the volume increase of the demineralized enamel was the highest in the control group, followed by fluoride varnish group and SDF group. The morphology of the enamel surface was the most rough and irregular in the control group, followed by fluoride varnish group and SDF group.