배양 상아질모세포 성장과 세포외 기질형성에 미치는 resveratrol의 효과
- Issued Date
- 2016
- Abstract
- Resveratrol (3,4',5,-trihydroxystilbene), a phytoalexin that is present in grapes, exerts a variety of actions to reduce superoxides, prevent diabetes mellitus and inhibit inflammation. Furthermore, resveratrol acts as a chemopreventive agent and induces apoptotic cell death in various types of cancer cells. However, the role of resveratrol in odontoblastic cell differentiation is still unclear. In this study, therefore, the effect of resveratrol on regulating odontoblast differentiation was examined in MDPC-23 mouse odontoblastic cells derived from mouse dental papilla cells.
- Alternative Title
- Effect of resveratrol on cell growth and extra cellular matrix formation in cultured odontoblasts
- Alternative Author(s)
- Shin Sang Hun
- Affiliation
- 조선대학교 대학원
- Department
- 일반대학원 치의학과
- Advisor
- 김수관
- Awarded Date
- 2017-02
- Table Of Contents
- 표목차.................................................................................................................................................iii
도목차.................................................................................................................................................iv
ABSTRACT....................................................................................................................................v
I. 서론..................................................................................................................................................1
II. 실험재료 및 방법...................................................................................................................3
1. 실험재료........................................................................................................................................3
2. 세포주와 세포배양.....................................................................................................................3
3. Alizarine red-S 염색을 통한 골기질 형성 분석...............................................................4
4. 역전사 중합효소연쇄반응(RT-PCR) 분석...........................................................................4
5. MTT 분석에 의한 세포증식 측정.........................................................................................6
6. 실험자료의 통계학적 검정.......................................................................................................6
Ⅲ. 실험결과......................................................................................................................................7
1. MDPC-23 상아질모세포 분화과정에서 세포외 기질형성에 미치는
resveratrol의 효과.....................................................................................................................7
2. MDPC-23 상아질모세포 분화과정에서 분화 특이유전자들의 발현에 미치는
resveratrol의 효과.....................................................................................................................7
3. MDPC-23 상아질모세포 증식에 미치는 resveratrol의 효과..........................................9
Ⅳ. 총괄 및 고안.........................................................................................................................10
Ⅴ. 결론.............................................................................................................................................13
Ⅵ. 참고문헌...................................................................................................................................14
Ⅶ. 사진부도 설명.......................................................................................................................20
Ⅷ. 사진부도...................................................................................................................................23
- Degree
- Master
- Publisher
- 조선대학교 대학원
- Citation
- 신상훈. (2016). 배양 상아질모세포 성장과 세포외 기질형성에 미치는 resveratrol의 효과.
- Type
- Dissertation
- URI
- https://oak.chosun.ac.kr/handle/2020.oak/13106
http://chosun.dcollection.net/common/orgView/200000266018
- Appears in Collections:
- General Graduate School > 3. Theses(Master)
- Files in This Item:
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