은-시트레이트 나노로드 및 항균효과

Abstract

Silver has been known as biocidal materials for a long time. In 1800s’, AgNO3 solutions were frequently used in clinical space for the premature baby or the patient of burn wounds. However, their action mechanism is not still clear, and several plausible mechanisms have been suggested. Since many organic molecules also have antimicrobial activity, people expected some synergistic effect or complexes of silver and organic molecules. Recently, it has been reported that silver citrate complexes prepared in amorphous bulk can exhibit strong antimicrobial activity. Herein, we introduce antibiotic silver citrate nanorods, which are prepared by just mechanical stirring the mixture of AgNO3 and sodium citrate solutions. The silver citrate nanorods are characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffractometry (XRD). The silver citrate nanorods showed antimicrobial activity stronger than silver sulfadiazine which is generally used in clinical space.