다제내성 Acinetobacter baumannii 균주에 대한 Colistin, Tigecycline, Doripenem의 병합요법
- Author(s)
- 박균철
- Issued Date
- 2015
- Abstract
- The objective of this study is to evaluate the in vitro synergistic activity of colistin, tigecycline, and doripenem combinations against Multidrug-resistant (MDR) Acinetobacter baumannii. A total of 109 A. baumannii isolates including 60 non-XDR, 49 XDR strains were used in this study. In time kill assays, colistin plus doripenem, and colistin plus tigecycline combinations showed bactericidal synergy in ten (20.4%) and six (12.2%) isolates against XDR strains and eight (13.3%) and eighteen (30%) isolates against non-XDR strains, respectively. Antagonism was detected with the all antibiotic combinations, varied from 13.3~38.8%. These findings may add useful information to plan successful combination therapies for infections caused by XDR and non-XDR A.baumannii.
- Alternative Title
- Colistin, Tigecycline and Doripenem Combinations Against Multidrug-Resistant Acinetobacter baumannii
- Alternative Author(s)
- Park Gyun Cheol
- Affiliation
- 조선대학교 진단검사의학과
- Department
- 일반대학원 의학과
- Advisor
- 장숙진
- Awarded Date
- 2015-08
- Table Of Contents
- Ⅰ. 서론·················································································1
Ⅱ. 연구 및 대상방법····························································2
A. 대상··················································2
B. 항생제 감수성 검사································2
C. 시간-살균 검사·····································3
D. 통계 분석···········································3
Ⅲ. 결과·················································································4
A. 항생제 감수성 검사 결과···························4
B. 시간-살균 검사 결과·································4
Ⅳ. 고찰·················································································7
【참고문헌】·········································································10
- Degree
- Master
- Publisher
- 조선대학교
- Citation
- 박균철. (2015). 다제내성 Acinetobacter baumannii 균주에 대한 Colistin, Tigecycline, Doripenem의 병합요법.
- Type
- Dissertation
- URI
- https://oak.chosun.ac.kr/handle/2020.oak/12500
http://chosun.dcollection.net/common/orgView/200000265002
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Appears in Collections:
- General Graduate School > 3. Theses(Master)
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