천일염 함유 구강세정제의 치은염과 구취 개선 효과에 관한 연구

Abstract

Objectives: The goal of mouth washing is to prevent and treat periodontal diseases through the selective antibiotic ability against oral bacteria. As a folk remedy, salt has been used for anti-inflammatory activity and mouthwash. And the most commercial mouthwashes also contain a little salt. The object of this study is to evaluate the clinical effect of a sun-dried salt containing mouthwash with or without natural materials on gingivitis and halitosis.

Subjects and Methods: 120 subjects participated in this study and were randomly selected into 3 groups (2 experimental groups and a control group). A total of 77 subjects(except the 43 dropout patients) conducted a clinical trial(distilled water; 26 control group subjects, sun-dried slat; 25 experimental group A subjects, sun-dried salt with natural materials; 26 experimental group B subjects). Natural materials used in this study were Opuntia humifusa extract, green tea extract, Laurus nobilis leaf extract, and mint extract. The mint extract was used for flavor. As a pre-treatment, the subjects stopped oral hygiene care for the first 3 days. During the experimental period, the subjects used the appropriate mouthwash for 30 seconds, 15ml/time, 3 times/day for 1 week. At baseline and 1 week, 5 parameters(gingival index, sulcus bleeding index, plaque index, gingival cervical fluid(GCF), halitosis index) were assessed.

Result: In the control group, the gingival index(GI) showed a statistically significant average increase of 0.22 at 1 week compared to baseline(P<0.05). But the experimental group A decreased by 0.09 and the experimental group B decreased by 0.12, and there was no statistically significant difference between the two groups. The decrease in plaque index(PI) by 0.02 was detected between values at baseline and 1 week, but there was no statistically significant difference in the control group. Furthermore, the experimental group A showed a statistically significant increase in PI by 0.52. On the other hand, a decrease of 0.40 for the experimental group B did not reach statistical significance(P<0.01). Regarding sulcus bleeding index(SBI), statistical significance was detected between values at baseline and 1 week for the control group(P<0.01). However, the experimental group A and the experimental group B showed a decrease by 0.40 and 0.03 respectively, but there was no statistical significance. In the halitosis index(HI), at 1 week, the control group and the experimental group B both resulted in an increase of 1.27 and 0.19 respectively, compared to baseline, but only the control group had statistically significant difference(P<0.01). The experimental group A resulted in a decrease of 0.32 but did not reach statistical significance. At 1week evaluation, in the control group, the increase at #16(FDI tooth notation) gingival cervical fluid(GCF) by 11.9 compared to baseline did not reach statistical significance, but the increase at #36 by 22.39 had statistical significance. The experimental group A showed a decrease of 28.96 at #16 (P<0.05), and a decrease of 42.48 at #36 and both groups had statistical significance. And in the experimental group B, the decrease of 5.19 at #16 did not reach statistical significance, but at #36, there was a significant decrease of 32.27(P<0.01).

Conclusion: A sun-dried salt containing mouthwash and a sun-dried salt with natural materials containing mouthwash had a clinical effect on antigingivitis and reducing halitosis. However they could not inhibit plaque accumulation.

Key words: sun-dried salt, mouthwash, gingivitis, halitosis