I형 교원질이 피복된 비계물질의 세포부착에 관한 주사전자현미경적 평가

Abstract

The scaffold surface can be altered by surface coating materials. We evaluated the effect of a collagen type I coating on scaffold materials(Bio-Oss block bone, Geistlich, Swiss). Mongrel dog bone marrow stromal cells obtained from iliac bone were used to evaluate the cell morphology via scanning electron microscopy(SEM). They were cultured for 1-, 2- and 3-week, respectively. The surface of collagen-coated scaffold materials showed more smooth than that of collagen non-coated materials and the dendritic shape characteristic of cell adhesion with the lapse of culture time. So, author conclude that an scaffold materials coated with collagen type I stimulated the adhesion of mongrel dog bone marrow stem cells. In the future, the research is needed to evaluate the vertical alveolar ridge augmentation in vivo.