저압 및 대기압 플라즈마에 의한 고분자 생체재료의 표면개질 효과

Abstract

Plasma surface modification are commonly used to improve the surface of biomaterials. High density polyethylene (HDPE) and expanded polytetrafluoroethylene (e-PTFE) have hydrophobic surface properties. In this study, hydrophobic 3D HDPE scaffold and e-PTFE were surface modified by low and atmospheric pressure plasma treatment to enhance the preosteoblast cell adhesion, proliferation and differentiation. After plasma treatment, HDPE and e-PTFE surface characterization were investigated and biological evaluation was determined by preosteoblast cell. Results from this investigation showed that plasma treated 3D HDPE scaffold and e-PTFE increased hydrophilic properties also plasma treated 3D HDPE scaffold and e-PTFE improved biocompatibility. Low and atmospheric pressure plasma treatment technology was provide good biocompatibility for bone tissue engineering application.